Rotamerically Induced PerturbationsLarge perturbations
Response to RIP in tim-closed
deviations averaged over the 10th ps of simulation
background temperature = 300k
rotational temperature = 300k
significant response defined by Cα-RMSD deviation > 6 Å
PDB accession code: 1TPH
column = Cα-RMSD response to a RIP simulation
susceptibility of response to RIP of neighbors
no. of responding residues for each RIP
averaged Cα-RMSD fluctuations above background


Last snapshot of trajectory where Cα-RMSD is indicated by redness and thickness of chain.
ARG-1 [4]
LYS-2 [5]
PHE-3 [6]
PHE-4 [7]
VAL-5 [8]
ASN-8 [11]
TRP-9 [12]
LYS-10 [13]
MET-11 [14]
ASN-12 [15]
ASP-14 [17]
LYS-15 [18]
LYS-16 [19]
SER-17 [20]
LEU-18 [21]
GLU-20 [23]
LEU-21 [24]
ILE-22 [25]
HIS-23 [26]
THR-24 [27]
LEU-25 [28]
ASN-26 [29]
LYS-29 [32]
LEU-30 [33]
SER-31 [34]
ASP-33 [36]
THR-34 [37]
GLU-35 [38]
VAL-36 [39]
VAL-37 [40]
CYS-38 [41]
SER-42 [45]
ILE-43 [46]
TYR-44 [47]
LEU-45 [48]
ASP-46 [49]
PHE-47 [50]
ARG-49 [52]
GLN-50 [53]
LYS-51 [54]
LEU-52 [55]
ASP-53 [56]
LYS-55 [58]
ILE-56 [59]
VAL-58 [61]
GLN-61 [64]
ASN-62 [65]
CYS-63 [66]
TYR-64 [67]
LYS-65 [68]
VAL-66 [69]
LYS-68 [71]
PHE-71 [74]
THR-72 [75]
GLU-74 [77]
ILE-75 [78]
SER-76 [79]
MET-79 [82]
ILE-80 [83]
LYS-81 [84]
ASP-82 [85]
ILE-83 [86]
TRP-87 [90]
VAL-88 [91]
ILE-89 [92]
LEU-90 [93]
HIS-92 [95]
SER-93 [96]
GLU-94 [97]
ARG-95 [98]
ARG-96 [99]
HIS-97 [100]
VAL-98 [101]
PHE-99 [102]
GLU-101 [104]
SER-102 [105]
ASP-103 [106]
GLU-104 [107]
LEU-105 [108]
ILE-106 [109]
GLN-108 [111]
LYS-109 [112]
VAL-110 [113]
HIS-112 [115]
LEU-114 [117]
GLU-116 [119]
LEU-118 [121]
VAL-120 [123]
ILE-121 [124]
CYS-123 [126]
ILE-124 [127]
GLU-126 [129]
LYS-127 [130]
LEU-128 [131]
ASP-129 [132]
GLU-130 [133]
ARG-131 [134]
GLU-132 [135]
ILE-135 [138]
THR-136 [139]
GLU-137 [140]
LYS-138 [141]
VAL-139 [142]
VAL-140 [143]
PHE-141 [144]
GLU-142 [145]
GLN-143 [146]
THR-144 [147]
LYS-145 [148]
ILE-147 [150]
ASP-149 [152]
ASN-150 [153]
VAL-151 [154]
LYS-152 [155]
ASP-153 [156]
TRP-154 [157]
SER-155 [158]
LYS-156 [159]
VAL-157 [160]
VAL-158 [161]
LEU-159 [162]
TYR-161 [164]
GLU-162 [165]
VAL-164 [167]
TRP-165 [168]
ILE-167 [170]
THR-169 [172]
LYS-171 [174]
THR-172 [175]
THR-174 [177]
GLN-176 [179]
GLN-177 [180]
GLN-179 [182]
GLU-180 [183]
VAL-181 [184]
HIS-182 [185]
GLU-183 [186]
LYS-184 [187]
LEU-185 [188]
ARG-186 [189]
TRP-188 [191]
LEU-189 [192]
LYS-190 [193]
THR-191 [194]
HIS-192 [195]
VAL-193 [196]
SER-194 [197]
ASP-195 [198]
VAL-197 [200]
GLN-199 [202]
SER-200 [203]
THR-201 [204]
ARG-202 [205]
ILE-203 [206]
ILE-204 [207]
TYR-205 [208]
SER-208 [211]
VAL-209 [212]
THR-210 [213]
ASN-213 [216]
CYS-214 [217]
LYS-215 [218]
GLU-216 [219]
LEU-217 [220]
SER-219 [222]
GLN-220 [223]
HIS-221 [224]
ASP-222 [225]
VAL-223 [226]
ASP-224 [227]
PHE-226 [229]
LEU-227 [230]
VAL-228 [231]
SER-232 [235]
LEU-233 [236]
LYS-234 [237]
GLU-236 [239]
PHE-237 [240]
VAL-238 [241]
ASP-239 [242]
ILE-240 [243]
ILE-241 [244]
ASN-242 [245]
LYS-244 [247]
HIS-245 [248]